You can lose weight on the Mediterranean Diet. New research coming from the now known PREDIMED study, a long-term nutritional intervention study aimed to assess the efficacy of the Mediterranean diet in the primary prevention of cardiovascular diseases, showed that people lost slightly more weight when following a Mediterranean diet, compared to a low-fat diet. They also had the least increase in waist circumference compared to the low-fat diet. Of course this is not the first time the Mediterranean diet has been associated with weight loss, another study in 2008 published in the New England Journal of Medicine also showed that there was greater weight loss with the Mediterranean diet compared to a low-fat diet. Other studies have also associated the Mediterranean diet with a healthy weight in children as well as in pregnant women.